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Peter Hillmen Selected Research

ofatumumab

1/2020Efficacy and Safety of Duvelisib Following Disease Progression on Ofatumumab in Patients with Relapsed/Refractory CLL or SLL in the DUO Crossover Extension Study.
12/2018The phase 3 DUO trial: duvelisib vs ofatumumab in relapsed and refractory CLL/SLL.
12/2018Improvement in Parameters of Hematologic and Immunologic Function and Patient Well-being in the Phase III RESONATE Study of Ibrutinib Versus Ofatumumab in Patients With Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma.
11/2018Single-agent ibrutinib versus chemoimmunotherapy regimens for treatment-naïve patients with chronic lymphocytic leukemia: A cross-trial comparison of phase 3 studies.
9/2016Health-related quality of life and patient-reported outcomes of ofatumumab plus chlorambucil versus chlorambucil monotherapy in the COMPLEMENT 1 trial of patients with previously untreated CLL.
8/2015Ofatumumab monotherapy in fludarabine-refractory chronic lymphocytic leukemia: final results from a pivotal study.
5/2015Chlorambucil plus ofatumumab versus chlorambucil alone in previously untreated patients with chronic lymphocytic leukaemia (COMPLEMENT 1): a randomised, multicentre, open-label phase 3 trial.
4/2015Ofatumumab in poor-prognosis chronic lymphocytic leukemia: a phase IV, non-interventional, observational study from the European Research Initiative on Chronic Lymphocytic Leukemia.
7/2014Ibrutinib versus ofatumumab in previously treated chronic lymphoid leukemia.
4/2010Ofatumumab as single-agent CD20 immunotherapy in fludarabine-refractory chronic lymphocytic leukemia.

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Peter Hillmen Research Topics

Disease

76B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
01/2022 - 01/2002
26Paroxysmal Hemoglobinuria (Paroxysmal Nocturnal Hemoglobinuria)
09/2022 - 05/2002
24Hemolysis
09/2022 - 01/2002
19Neoplasms (Cancer)
11/2021 - 01/2002
15Residual Neoplasm
11/2021 - 03/2004
14Disease Progression
01/2022 - 03/2004
14Infections
11/2021 - 01/2002
13Fatigue
09/2022 - 09/2006
9Diarrhea
01/2021 - 07/2014
8Thrombosis (Thrombus)
01/2020 - 11/2003
8Neutropenia
01/2019 - 05/2015
6Atrial Fibrillation
11/2021 - 03/2015
6Hemorrhage
01/2021 - 11/2003
6Lymphocytosis
01/2020 - 12/2007
5Anemia
09/2022 - 04/2005
5Hypertension (High Blood Pressure)
12/2019 - 05/2010
5Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
10/2018 - 04/2005
4Non-Hodgkin Lymphoma (Lymphosarcoma)
01/2021 - 08/2003
4Chronic Disease (Chronic Diseases)
01/2021 - 09/2006
4Cough
01/2019 - 07/2014
4Nausea
12/2018 - 12/2007
4Pulmonary Hypertension
07/2013 - 04/2005
3Abdominal Pain (Pain, Abdominal)
09/2022 - 05/2007
3Hemoglobinuria
09/2022 - 02/2004
3Leukemia
12/2020 - 02/2006
3Fever (Fevers)
12/2018 - 07/2014
3Cytopenia
12/2013 - 01/2002
2Deglutition Disorders (Dysphagia)
09/2022 - 05/2007
2Erectile Dysfunction
09/2022 - 05/2007
2Headache (Headaches)
01/2021 - 01/2019
2Aplastic Anemia (Anemia, Hypoplastic)
11/2019 - 01/2018
2B-Cell Lymphoma (Lymphoma, B Cell)
05/2019 - 01/2018
2Pneumonia (Pneumonitis)
01/2019 - 01/2017
2Hematologic Neoplasms (Hematological Malignancy)
12/2018 - 03/2002
2Tumor Lysis Syndrome
12/2018 - 03/2018
2Febrile Neutropenia
03/2018 - 01/2017
2Thrombocytopenia (Thrombopenia)
01/2017 - 02/2008
2Lymphadenopathy
01/2017 - 04/2010
2Vomiting
12/2015 - 12/2007
2Lymphoid Leukemia
07/2014 - 01/2004
2Chronic Renal Insufficiency
07/2013 - 08/2010
1Dyspnea (Shortness of Breath)
09/2022
1Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
12/2021
1Atrial Flutter (Flutter, Atrial)
11/2021
1Injection Site Reaction
01/2021
1COVID-19
10/2020
1Spontaneous Remission
01/2020

Drug/Important Bio-Agent (IBA)

35ibrutinibIBA
01/2022 - 07/2014
26eculizumabFDA Link
09/2022 - 02/2004
18Agammaglobulinaemia Tyrosine KinaseIBA
01/2022 - 01/2016
16Rituximab (Mabthera)FDA Link
01/2022 - 02/2004
13Complement System Proteins (Complement)IBA
01/2021 - 01/2002
13Alemtuzumab (Campath)FDA Link
01/2017 - 01/2002
12fludarabineIBA
01/2022 - 03/2002
10ofatumumabFDA Link
01/2020 - 04/2010
9Chlorambucil (Leukeran)FDA Link
01/2022 - 12/2007
9acalabrutinibIBA
01/2022 - 01/2016
8idelalisibIBA
01/2021 - 03/2014
7venetoclaxIBA
12/2020 - 01/2018
5Bendamustine HydrochlorideFDA Link
01/2022 - 01/2017
5Cyclophosphamide (Cytoxan)FDA LinkGeneric
01/2022 - 04/2005
5Glycosylphosphatidylinositols (Glycosyl-Phosphatidylinositol)IBA
08/2021 - 05/2002
5L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
07/2013 - 10/2005
4Biological ProductsIBA
01/2020 - 01/2004
4Proteins (Proteins, Gene)FDA Link
03/2018 - 01/2002
4Nitric Oxide (Nitrogen Monoxide)FDA Link
08/2012 - 04/2005
4Monoclonal AntibodiesIBA
06/2011 - 03/2002
4Complement Inactivating AgentsIBA
08/2010 - 09/2006
3zanubrutinibIBA
01/2022 - 04/2020
3serum P-component (CIt)IBA
10/2021 - 11/2018
3GPI-Linked ProteinsIBA
08/2021 - 01/2004
3Pharmaceutical PreparationsIBA
01/2021 - 10/2016
3Hemoglobins (Hemoglobin)IBA
01/2021 - 04/2005
3Immunoglobulin Heavy Chains (Immunoglobulin Heavy Chain)IBA
11/2019 - 12/2007
2TESIBA
09/2022 - 07/2013
2Transaminases (Aminotransferases)IBA
12/2020 - 01/2019
2duvelisibIBA
01/2020 - 12/2018
2Biomarkers (Surrogate Marker)IBA
05/2019 - 08/2012
2AntibodiesIBA
03/2016 - 01/2004
2Lenalidomide (CC 5013)FDA Link
01/2016 - 03/2012
2pro-brain natriuretic peptide (1-76)IBA
08/2012 - 05/2010
2Brain Natriuretic Peptide (Natrecor)FDA Link
08/2012 - 05/2010
2Warfarin (Coumadin)FDA LinkGeneric
06/2011 - 11/2003
2Alkylating AgentsIBA
09/2007 - 05/2002
2purineIBA
01/2004 - 08/2003
1Indicators and Reagents (Reagents)IBA
11/2021
1Peptides (Polypeptides)IBA
01/2021
1ravulizumabIBA
01/2021
1pegcetacoplanIBA
01/2021
1forodesineIBA
12/2020
1deoxyguanosine triphosphate (dGTP)IBA
12/2020
1FibrinIBA
01/2020
16- (1H- indazol- 6- yl)- N- (4- morpholinophenyl)imidazo(1,2- a)pyrazin- 8- amineIBA
01/2020
1tirabrutinibIBA
01/2020
1Immunoglobulin Variable RegionIBA
01/2020

Therapy/Procedure

46Therapeutics
01/2022 - 03/2002
8Drug Therapy (Chemotherapy)
11/2019 - 03/2002
3Aftercare (After-Treatment)
01/2017 - 05/2002
2Blood Transfusion (Blood Transfusions)
12/2013 - 01/2009
1Precision Medicine
12/2020